Electrophysiological Methods in Biological ResearchElectrophysiological Methods in Biological Research, Third Revised Edition describes the principles and applications of significant electrophysiological methods as regards to transistorisation of electrophysiological apparatus and to the mathematical analysis of electrophysiological data. The book explains the aspects of physics and electronics that are important in electrophysiology, such as the basic principles of semiconductor function, electronic simulators, electrodes, and the processing of electrophysiological data. The text also cites several examples that measure the resulting membrane potential if one electrode is inside the cell while the other is in contact with the cell's surface. Other experiments show the electrophysiological techniques and the fundamentals of electrical activity in the peripheral excitable structures, and its association with physiological functions. In considering the problems of nerve and muscle physiology, the investigator should know the technique of recording the electrical signs of a nerve impulse. These signs, or action potentials, indicate the presence of a nerve impulse. The text also discusses the effects of barbiturates or ether anesthesia in EEG activity, as well as its dissociation after physostigmine and atropine have been administered. The book can prove useful for pharmacologists, microchemists, cellular biologists, and research workers and technologists dealing with neural mechanisms. |
Contents
13 | |
15 | |
17 | |
23 | |
40 | |
CHAPTER III General electrophysiology of cells and tissues | 271 |
CHAPTER IV Electrophysiology of isolated excitable structures In vitro | 304 |
CHAPTER V Electrophysiology of peripheral excitable structures In situ | 387 |
CHAPTER VIII Electrophysiology of the spinal cord | 471 |
CHAPTER IX Electrophysiology of the cerebral cortex | 507 |
CHAPTER X Electrophysiology of subcortlcal structures | 586 |
Stereotaxic atlases for the cat rabbit and rat | 653 |
Mathematical terms | 732 |
747 | |
Author index | 790 |
801 | |
CHAPTER VI Electrophysiology of peripheral synoptic junctions | 405 |
CHAPTER VII Electrophysiology of sensory receptors | 445 |
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Common terms and phrases
action potential activity afferent Ag-AgCl amplifier amplitude anaesthesia anode anode current anode voltage apparatus applied axon beam brain c/sec calibration capacitance cathode cathode follower cathode-ray oscilloscope cell cerebral cortex changes circuit coil condenser connected constant cord corresponding cortical crayfish decreases depolarization determined diameter discharge Eccles electrical electrophysiological electrotonic end-plate equation evoked excitability experiment frequency frog function ganglion grid current grid voltage hippocampus increase inhibitory input interval intracellular ions measured membrane potential microelectrode motoneurone msec multivibrator muscle fibre needle negative nerve fibres nerve impulse nervous neurons Neurophysiol noise nucleus obtained oscillator oscilloscope output phase Physiol polarity positive postsynaptic potential difference presynaptic produced recording electrodes resistance resistor response Ringer solution sciatic nerve screen screen grid sensory shown in Fig signal spike spinal spreading depression stereotaxic stimulating electrodes strychnine surface synaptic potential synchronised tissue transistor trephine tube usually valve ventral roots voltage wave