The Ischemic PenumbraGeoffrey A. Donnan, Jean-Claude Baron, Stephen M. Davis, Frank R. Sharp The Ischemic Penumbra presents the current status of concepts and research on this topic and identifies the latest methods for clinicians to quickly and efficiently recognize viable cerebral tissue for enhanced stroke management. Focusing on state-of-the-science technologies and current trends, the book examines imaging strategies utilizing PET, SP |
Contents
| 1 | |
Overview Definition and Criteria | 7 |
Chapter 3 Perfusion Thresholds in Cerebral Ischemia | 21 |
Chapter 4 Duration and Thresholds of the Ischemic Penumbra in Different Species | 37 |
Events Within the Penumbra | 59 |
Chapter 6 Multimodal Mapping of the Ischemic Penumbra in Animal Models | 77 |
Chapter 7 Molecular Biology of the Penumbra | 93 |
Chapter 8 Selective Neuronal Loss | 109 |
Chapter 13 Magnetic Resonance Imaging Assessment of the Ischemic Penumbra in Experimental Stroke | 177 |
Chapter 14 Penumbra Imaged with Magnetic Resonance Imaging in Humans | 187 |
Current Status and Implications for Therapy | 197 |
New Techniques | 219 |
Chapter 17 ClinicalImaging Mismatch as an Index of the Penumbra | 241 |
Chapter 18 The Topography of the Ischemic Penumbra | 251 |
Chapter 19 The Penumbra and Intracerebral Hemorrhage | 263 |
THE ISCHEMIC PENUMBRA IMPLICATIONS FOR THERAPY | 281 |
Chapter 9 Inflammation and Reperfusion Injury Within the Penumbra | 125 |
IMAGING THE PENUMBRA OTHER APPROACHES | 137 |
Positron Emission Tomography Fluoromisonidazole | 149 |
Chapter 12 Can the Penumbra Be Imaged Using SinglePhoton Emission Computed Tomography? | 165 |
Other editions - View all
The Ischemic Penumbra Geoffrey A. Donnan,Jean-Claude Baron,Stephen M. Davis,Frank R. Sharp No preview available - 2007 |
Common terms and phrases
activator acute ischemic stroke acute stroke analysis animal appears approach assessment associated binding Blood Flow Metab brain cell cerebral artery occlusion cerebral blood flow changes clinical combined compared core correlation cortex cortical damage death decreased deficit defined demonstrated developed diffusion early effect et al evolution experimental expression FIGURE final focal focal cerebral ischemia function g/min gene glucose hemorrhage human hypoxic increased indicated induced infarction initial injury ischemic penumbra lesion levels magnetic resonance imaging maps marker measured mechanisms metabolic method middle cerebral artery minutes mismatch neurological neuronal neuroprotective normal observed occur onset outcome oxygen patients perfusion potential predict progression protein reduced region reperfusion reported response selective severe showed shown signal significant SPECT stroke patients studies suggesting technique therapeutic therapy thresholds thrombolysis tissue transient treatment trial University values volume window